Validation of "prodromal" criteria to detect individuals at ultra high risk of psychosis: 2 year follow-up

AR Yung; B Nelson; C Stanford; MB Simmons; EM Cosgrave; E Killackey; LJ Phillips; A Bechdolf; J Buckby; PD McGorry

Journal article

Validation of "prodromal" criteria to detect individuals at ultra high risk of psychosis: 2 year follow-up

AR Yung, B Nelson, C Stanford, MB Simmons, EM Cosgrave, E Killackey, LJ Phillips, A Bechdolf, J Buckby, PD McGorry

Schizophrenia Research | ELSEVIER | Published : 2008

DOI: 10.1016/j.schres.2008.07.012

Abstract

Background: Identification of individuals "prodromal" for schizophrenia and other psychotic disorders relies on criteria that predict onset within a brief period. Previous trials and biological research have been predicated on the view that certain "ultra high risk" (UHR) criteria detect "the prodrome", but there is a need to test the validity of these criteria. Aim: To assess the predictive validity of the UHR criteria in a clinical population. Method: The presence of UHR criteria was determined in 292 help-seeking individuals. At 2 year follow-up the number of new cases of psychotic disorder was assessed. Results: The criteria significantly predicted onset of psychotic disorder within 2 ye..

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University of Melbourne Researchers

Barnaby Nelson Author

Magenta Simmons Author

Eoin Killackey Author

Lisa Phillips Author

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Grants

Awarded by National Health and Medical Research (NHMRC) Program

Funding Acknowledgements

All authors gratefully acknowledge the National Health and Medical Research (NHMRC) Program Grant (#350241) and the Colonial Foundation which provided funding for this study. We also thank the young people who participated.